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Last updated on 2025-01-07.

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Peng Zhou

Investigator at Institute of Crop Sciences, Chinese Academy of Agricultural Sciences (CAAS). Using a combination of classical genetics, comparative genomics and multi-omics approaches, I work to understand the regulatory mechanism of gene expression during plant development and under stress conditions, identify key cis-regulatory elements and transcription factors for crop improvement. My research interests also include constructing plant gene regulatory networks, training machine learning models to predict temporal/spatial gene expression patterns, as well as understanding the molecular mechanism of heterosis.

Education

Ph.D. Plant Pathology & Bioinformatics

University of Minnesota, Twin Cities

St. Paul US

2015 - 2009

  • Advidor: Nevin D. Young

M.S. Forensic Genetics

Xi’an Jiaotong University

Xi’an CN

2009 - 2007

B.E. Biological Engineering & Computer Science

Xi’an Jiaotong University

Xi’an CN

2007 - 2003

Research Experience

Investigator & Professor

Institute of Crop Sciences, Chinese Academy of Agricultural Sciences (CAAS)

Beijing CN

present - 2021

Post Doctoral Associate

University of Minnesota, Twin Cities

St. Paul US

2021 - 2016

  • Advisor: Nathan M. Springer

AgroInformatics Analyst

University of Minnesota, Twin Cities

St. Paul US

2016 - 2015

Representative Publications

A complete assembly of the sorghum BTx623 reference genome

Plant Commun. 2024, 5: 100977.

N/A

2024

  • Deng Y*, Zhou P*, Li F*, Wang J*, Xie K*, Liang H, Wang C, Liu B, Zhu Z, Zhou W, et al

Prediction of conserved and variable heat and cold stress response in maize using cis-regulatory information

Plant Cell. 2022, 34: 514-534.

N/A

2022

  • Zhou P, Enders TA, Myers ZA, Magnusson E, Crisp PA, Noshay J, …, Springer NM
  • Impact Factor = 11.277

Meta Gene Regulatory Networks in Maize Highlight Functionally Relevant Regulatory Interactions

Plant Cell. 2020, 32: 1377-1396.

N/A

2020

  • Zhou P, Li Z, Magnusson E, Cano FAG, Crisp PA, Noshay J, Grotewold E, HirschC, Briggs SP, Springer NM
  • Impact Factor = 11.277

Dynamic Patterns of Gene Expression Additivity and Regulatory Variation throughout Maize Development

Molecular Plant. 2019, 12: 410-425.

N/A

2019

  • Zhou P, Hirsch CN, Briggs SP, Springer NM
  • Impact Factor = 10.812

Exploring structural variation and gene family architecture with De Novo assemblies of 15 Medicago genomes

BMC Genomics. 2017, 18: 261.

N/A

2017

  • Zhou P, Silverstein KAT, Ramaraj T, Guhlin J, Denny R, Liu J, …, Young ND

Other Publications

  • Citation = 3430
  • H-index = 22
  • I10-index = 29

Transcriptome profiling of maize transcription factor mutants to probe gene regulatory network predictions

G3. 2024:jkae274.

N/A

2024

  • Ellison EL, Zhou P, Chu Y-H, Hermanson P, Gomez-Cano L, Myers ZA, Abnave A, Gray J, Hirsch CN, Grotewold E, Springer NM

Intraspecific diploidization of a halophyte root fungus drives heterosis

Nat Commun. 2024:15(1):5872.

N/A

  • Li Z, Zhu Z, Qian K, Tang B, Han B, Zhong Z, Fu T, Zhou P#, Stukenbrock EH, Martin FM#, Yuan Z#

Mutator transposon insertions within maize genes often provide a novel outward reading promoter

Genetics. 2023:225(3):iyad171.

N/A

2023

  • Ellison EL, Zhou P, Hermanson P, Chu Y-H, Read A, Hirsch CN, Grotewold E, Springer NM.

Transcriptome Analysis of Developing Wheat Grains at Rapid Expanding Phase Reveals Dynamic Gene Expression Patterns

Biology. 2022, 11: 281.

N/A

2022

  • Guan J, Wang Z, Liu S, Kong X, Wang F, Sun G, Geng S, Mao L#, Zhou P#, Li A#

Plant height heterosis is quantitatively associated with expression levels of plastid ribosomal proteins

Proc Natl Acad Sci U S A.. 2021. 118 (47) e2109332118.

N/A

2021

  • Birdseye D, de Boer LA, Bai H, Zhou P, Shen Z, Schmelz EA, Springer NM, Briggs SP

Widespread imprinting of transposable elements and young genes in the maize endosperm

PLoS Genetics. 2021;17: e1009491.

N/A

  • Anderson SN, Zhou P, Higgins K, Brandvain Y, Springer NM

Assessing the regulatory potential of transposable elements using chromatin accessibility profiles of maize transposons

Genetics. 2021, 217: 1–13.

N/A

  • Noshay JM, Marand AP, Anderson SN, Zhou P, Guerra MKM, Lu Z, et al

Single-parent expression drives dynamic gene expression complementation in maize hybrids

Plant Journal. 2021, 105: 93–107.

N/A

  • Li Z, Zhou P, Della Coletta R, Zhang T, Brohammer AB, H O’Connor C, et al.

The antagonistic MYB paralogs RH1 and RH2 govern anthocyanin leaf markings in Medicago truncatula

New Phytologist. 2021, 229: 3330–3344.

N/A

  • Wang C, Ji W, Liu Y, Zhou P, Meng Y, Zhang P, et al.

Stable unmethylated DNA demarcates expressed genes and their cis-regulatory space in plant genomes

Proc Natl Acad Sci U S A.. 2020, 117: 23991–24000.

N/A

2020

  • Crisp PA, Marand AP, Noshay JM, Zhou P, Lu Z, Schmitz RJ, et al.

Variation and Inheritance of Small RNAs in Maize Inbreds and F1 Hybrids

Plant Physiol. 2020, 182: 318-331.

N/A

  • Crisp PA, Hammond R, Zhou P, Vaillancourt B, Lipzen A, Daum C, et al

Monitoring the interplay between transposable element families and DNA methylation in maize

PLoS Genetics. 2019, 15: e1008291.

N/A

2019

  • Noshay JM, Anderson SN, Zhou P, Ji L, Ricci W, Lu Z, et al

Transposable elements contribute to dynamic genome content in maize

Plant Journal. 2019, 100: 1052-1065.

N/A

  • Anderson SN, Stitzer MC, Brohammer AB, Zhou P, Noshay JM, O’Connor CH, et al

Strategies for optimizing BioNano and Dovetail explored through a second reference quality assembly for the legume model

BMC Genomics. 2017, 18: 578.

N/A

2017

  • Moll KM*, Zhou P*, Ramaraj T, Fajardo D, Devitt NP, Sadowsky MJ, et al

Hybrid assembly with long and short reads improves discovery of gene family expansions

BMC Genomics. 2017, 18: 541.

N/A

  • Miller JR, Zhou P, Mudge J, Gurtowski J, Lee H, Ramaraj T, et al

Exploring structural variants in environmentally sensitive gene families

Curr Opin Plant Biol. 2016, 30: 19–24.

N/A

2016

  • Young ND, Zhou P, Silverstein KA

Genomic signature of adaptation to climate in Medicago truncatula

Genetics. 2014, 196: 1263–1275.

N/A

2014

  • Yoder JB, Stanton-Geddes J, Zhou P, Briskine R, Young ND, Tiffin P

Selection, genome-wide fitness effects and evolutionary rates in the model legume Medicago truncatula

Molecular Ecology. 2011, 108: E864-70.

N/A

2013

  • Paape T, Bataillon T, Zhou P, J Y Kono T, Briskine R, Young ND, et al

Detecting small plant peptides using SPADA (Small Peptide Alignment Discovery Application)

BMC Bioinformatics. 2013, 14: 335.

N/A

  • Zhou P, Silverstein KA, Gao L, Walton JD, Nallu S, Guhlin J, et al

Whole-genome nucleotide diversity, recombination, and linkage disequilibrium in the model legume Medicago truncatula

Proc Natl Acad Sci U S A. 2013, 22: 3525–3538.

N/A

  • Branca A, Paape TD, Zhou P, Briskine R, Farmer AD, Mudge J, et al

Fine-scale population recombination rates, hotspots, and correlates of recombination in the Medicago truncatula genome)

Genome Biol Evol. 2012, 4: 726–737.

N/A

2012

  • Paape T, Zhou P, Branca A, Briskine R, Young N, Tiffin P

The Medicago genome provides insight into the evolution of rhizobial symbioses

Nature. 2011, 480: 520-524.

N/A

2011

  • Young ND, Debellé F, Oldroyd GED, …, Zhou P, …, et al

Professional service

Reviewer for journals

N/A

N/A

  • Plant Biotechnology Journal
  • JIPB
  • Plant Physiology
  • BMC Biology
  • Crop Journal
  • The Plant Genome

Conference presentations

Meta gene regulatory networks in maize refine functionally relevant regulatory interactions

Plant and Animal Genome XXVIII Conference

San Diego, CA

2020

Exploring Functional Transcriptomics using Gene Regulatory Networks in Maize.

61st Annual Maize Genetics Conference

St. Louis, MO

2019

Documenting the Manifestations of Heterosis in Co-expression Networks for Maize

Plant and Animal Genome XXVI Conference

San Diego, CA

2018

The Medicago Pan-Genome Reveals Large-scale Variation

Plant and Animal Genome XXII Conference

San Diego, CA

2014

Detecting secreted peptides in plants using SPADA (Secreted Peptide Alignment Discovery Algorithm)

Plant and Animal Genome XXI Conference

San Diego, CA

2013

Population-Scale Deep Sequencing Reveals Extensive Structural Variation in Medicago species

Minnesota Supercomputing Institute Research Exhibition

Minneapolis, MN

2011

Genome Distribution and Population Genetics of Nodule-Specific Cysteine-Rich (NCR) Peptides in Medicago

Plant and Animal Genome XIX Conference

San Diego, CA

A Medicago truncatula Hapmap as a Platform for Exploring the Genetics of Symbiosis

Plant and Animal Genome XVIII Conference

San Diego, CA

2010

Invited Presentations/Seminars

Co-expression based Gene Regulatory Networks Predict Functional Interactions in Maize

N/A

China Agriculture University, Beijing

2019

Transcriptome Dynamics in Maize

N/A

Huazhong Agriculture University, Wuhan

Toward a Medicago Pan-genome: Assembling and Comparing Multiple Genomes

Medicago truncatula Workshop

Noble Research Institute, Ardmore

2016

Assembling and Comparing Multiple High-Quality Medicago Genomes

N/A

Chinese Academy of Agricultural Sciences (CAAS), Beijing